Feel better quickly with intranasal or IV ketamine!
- Complex Regional Pain Syndrome
Ketamine works by stimulating AMPA, which increases brain derived growth factor to stimulate the formation of new nerve connections. Another mechanism of action by which ketamine works is through blocking NDMA receptors to decrease glutamate and restore the balance between glutamate and GABA. Suicidal thoughts can subside in 4-24 hours for quick relief, with 70% of patients with depression noting a positive response.
Ketamine Nasal Spray
In March 2019, the FDA approved Spravato (esketamine) nasal spray for the treatment-resistant depression. Depression that is treatment-resistant means that there has been no response after trying at least two different antidepressant treatments at adequate doses for adequate durations.
The American Journal of Psychiatry published a meta-analysis in February 2018 reviewing the effect of a single dose of IV ketamine on depression. Ketamine was found to quickly decrease suicidal thoughts, within 1 day and for up to 1 week in depressed patients with suicidal ideation.*
*Am J Psychiatry. 2018 Feb 1;175(2):150-158. doi: 10.1176/appi.ajp.2017.
In May 2019, the American Journal of Psychiatry published a study comparing ketamine regimens, and found that repeated ketamine infusions have cumulative and sustained antidepressant effects.*
Am J Psychiatry. 2019 May 1;176(5):401-409. doi: 10.1176/appi.ajp.2018.18070834. Epub 2019 Mar 29.
Ketamine infusion can be very beneficial for improving mood and pain. Ketamine IV can be used occasionally as needed, though a common regimen for the infusion is three times a week for 2 weeks. Some people may require additional boosters once every 1-3 months to sustain the benefits. Appointments take approximately 2 hours. Weekend appointments are also available.
Intranasal ketamine spray can be used in conjunction with complementary therapies.
Common side effects, greater than 1% and less than 10%:
- nausea and vomiting
- vivid dreams and nightmares
- increased saliva production
- blurred vision
- increased heart rate and blood pressure during the infusion
- out of body experience during the infusion
- change in motor skills
IV Packages available:
First visit: $650
Other visits: $450
Package of 2: $800
Package of 4: $1400
Package of 6: $1900
Nasal Spray: $200 for visit
*prescription $0-$150, depending on insurance